Recombinant Human IL18BP
Catalog No : IGX-RP183
722.04€
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| Product name | Recombinant Human IL18BP | ||
|---|---|---|---|
| Catalog No | IGX-RP183 | ||
| Supplier’s Catalog No | IGX-RP183 | ||
| Supplier | ImuGeX | ||
| Source antigen | HEK cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 19 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | IL-18BP, Tadekinig-alfa<br/>Recombinant Human Interleukin-18 Binding Protein (IL18BP) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Recombinant IL-18BP is supplied as an 0.2 μm filtered PBS solution. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | IL-18BP is a secreted protein that binds IL-18 with high affinity and prevents its interaction with the IL-18R. Different isoforms of IL-18BP have been demonstrated, four in human and two in the murine system, and biological activity is limited to particular isoforms. IL-18 binding protein is a constitutively expressed and secreted protein that resembles the extracellular domains of Ig-like receptors but has no transmembrane form. Because IL-18 is one of the early signals leading to IFN-gamma production by Th1 cells, blocking IL-18 activity by IL-18BP may be involved in down-modulation of the early phases of immune responses. | ||
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