Recombinant Human NTF4
Catalog No : IGX-RP137
245.06€
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| Product name | Recombinant Human NTF4 | ||
|---|---|---|---|
| Catalog No | IGX-RP137 | ||
| Supplier’s Catalog No | IGX-RP137 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 14 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | NT-4, Neurotrophin-5, NT-5, Neutrophic factor 4, NTF5, NTF4<br/>Recombinant Human Neurotrophin-4 (NTF4) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Recombinant NT-4 was lyophilized from a 0.2 μm filtered PBS solution pH 7.5. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Neurotrophins are well-known retrograde signaling molecules that regulate differentiation and cell survival in many central and peripheral neurons. Neurotrophin-4 (NT-4) is the most recently discovered neurotrophic factor in mammals and, functionally, the least well understood. Little is known about the role of NT-4 in supporting the survival of identified classes of sensory neurons. Currently, the only available data are from cell counts of whole sensory ganglia. Mice lacking NT-4 (NT-4/) exhibit a loss of ~50% of the neurons in the nodose-petrosal and geniculate ganglia but no apparent loss of neurons in the dorsal root ganglia. | ||
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