Recombinant Human RANTES (CCL5)

Catalog No : IGX-RP117
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Product name Recombinant Human RANTES (CCL5)
Catalog No IGX-RP117
Supplier’s Catalog No IGX-RP117
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 9
Storage -70°C
Other names Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, T-cell-specific protein RANTES, D17S136E, SCYA5
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description RANTES belongs to the family of chemotactic cytokines known as chemokines and is expressed by an early response gene. The synthesis of RANTES is induced by TNF-alpha and IL-1-alpha. RANTES is chemotactic for T cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. RANTES also activates eosinophils to release eosinophilic cationic protein while being a potent activator of oxidative metabolism specific for eosinophils. RANTES increases the adherence of monocytes to endothelial cells and selectively supports the migration of monocytes and T lymphocytes expressing the cell surface markers CD4 and UCHL1.