Recombinant Human PTH

Catalog No : IGX-RP115
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Product name Recombinant Human PTH
Catalog No IGX-RP115
Supplier’s Catalog No IGX-RP115
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 9
Storage -70°C
Other names PTH, Parathormone, Parathyrin<br/>Recombinant Human Parathyroid Hormone (PTH)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Parathyroid hormone is a circulating hormone that acts as the central regulator of calcium metabolism by directly targeting bone, kidney, and intestine. The classical concept of PTH action is that it regulates serum calcium levels by stimulating bone resorption. However, intermittent administration of PTH selectively stimulates bone formation. It is now known that PTH binds to its receptor PTH1R, and activates the G protein alpha subunits. Besides PKA and PKC activation, PTH also regulates MAPKs including p42/p44 ERKs, p38, and c-Jun N-terminal kinase subtypes.