Recombinant Mouse IL3
Catalog No : IGX-RP083
245.06€
0.00€
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| Product name | Recombinant Mouse IL3 | ||
|---|---|---|---|
| Catalog No | IGX-RP083 | ||
| Supplier’s Catalog No | IGX-RP083 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Mouse | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 15 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | IL-3, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, Multi-CSF, HCGF, P-cell stimulation factor, Hematopoietic growth factor<br/>Recombinant Mouse Interleukin-3 (IL3) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in PBS | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | IL3 is produced mainly by T cells following cell activation by antigens and mitogens, but also by keratinocytes, natural killer cells, mast cells, endothelial cells, and monocytes. The analysis of bacterial-derived recombinant IL3 shows that glycosylation is not required for the activity of IL3. IL-3 sequences are evolutionarily less well conserved. Human and murine IL3 show approximately 29% homology at the protein level while murine and rat IL3 show approximately 54% homology. IL3 receptors are expressed on macrophages, mast cells, eosinophils, megakaryocytes, basophils, bone marrow progenitor cells, and various myeloid leukemia cells. Binding of IL3 to its receptor causes specific phosphorylation of a 150 kDa membrane glycoprotein. Recombinant mouse IL3 is a monomer of 15 kDa. | ||
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