Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-70°C
Other names			EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, MEGF7, EGF-L7, NOTCH4-like protein, Vascular endothelial statin, VE-statin, Zneu1<br/>Recombinant Human Epidermal Growth Factor-Like Protein 7 (EGFL7)
Grade			Highly Purified
Purity			>95% as determined by SDS-PAGE
Form			Recombinant Human EGFL7 is lyophilized from a 0.2 μm filtered solution (pH 7.0) in 100 mM glycine, 10 mM NaCl, 10% glycerol and 5% trehalose.
Reactivity life			6 months
Note			For reserch purpose only
Purity			>95% as determined by SDS-PAGE
Description			EGFL7 is an 31 kDa secreted protein that contains an Emilin-like (EMI) domain, and two epidermal growth factor (EGF) domains - one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble, similar to extracellular matrix (ECM) proteins and, thus, incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.