Recombinant Human FLT3 Ligand (FLT3LG)
Catalog No : IGX-RP039
253.43€
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| Product name | Recombinant Human FLT3 Ligand (FLT3LG) | ||
|---|---|---|---|
| Catalog No | IGX-RP039 | ||
| Supplier’s Catalog No | IGX-RP039 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 17.8 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | Fms-related tyrosine kinase 3 ligand, FLT3 ligand, FLT3LG, FLT3L | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered PBS solution pH 7.0 | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Known to bind to cells that express the tyrosine kinase receptor, FLT3LG promotes long-term expansion and differentiation of human pro-B cells. Human FLT3LG also stimulates the proliferation of cells expressing murine FLT-3 receptors. In combination with SCF and IL3, FLT3LG can cause expansion of cells with the marker spectrum CD34(+)/CD38(-). Alone, FLT3LG supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU-GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. FLT3LG has only marginal effects on progenitors for erythroid cells and megakaryocytes. Recombinant Human FLT3LG is a non-glycosylated, monomeric protein with intra-chain disulfide bonds. | ||
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